Showing results 131 - 140 out of 192
2009
Beltran-Alvarez, P., Arthur, C. J., Cox, R. J., Crosby, J., Crump, M. P., & Simpson, T. J. (2009). Preliminary kinetic analysis of acyl carrier protein-ketoacylsynthase interactions in the actinorhodin minimal polyketide synthase. Molecular BioSystems, 5(5), 511-518. https://doi.org/10.1039/b821844g
Cox, R. J., & Simpson, T. J. (2009). Chapter 3 Fungal Type I Polyketide Synthases. In D. Hopwood (Ed.), Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates (B ed., pp. 49-78). (Methods in Enzymology; Vol. 459, No. B). https://doi.org/10.1016/S0076-6879(09)04603-5
2008
Halo, L. M., Heneghan, M. N., Yakasai, A. A., Song, Z., Williams, K., Bailey, A. M., Cox, R. J., Lazarus, C. M., & Simpson, T. J. (2008). Late stage oxidations during the biosynthesis of the 2-pyridone tenellin in the entomopathogenic fungus beauveria bassiana. Journal of the American Chemical Society, 130(52), 17988-17996. https://doi.org/10.1021/ja807052c
Wu, J., Hothersall, J., Mazzetti, C., O'Connell, Y., Shields, J. A., Rahman, A. S., Cox, R. J., Crosby, J., Simpson, T. J., Thomas, C. M., & Willis, C. L. (2008). In vivo mutational analysis of the mupirocin gene cluster reveals labile points in the biosynthetic pathway: The "leaky hosepipe" mechanism. CHEMBIOCHEM, 9(9), 1500-1508. https://doi.org/10.1002/cbic.200800085
Halo, L. M., Marshall, J. W., Yakasai, A. A., Song, Z., Butts, C. P., Crump, M. P., Heneghan, M., Bailey, A. M., Simpson, T. J., Lazarus, C. M., & Cox, R. J. (2008). Authentic heterologous expression of the tenellin iterative polyketide synthase nonribosomal peptide synthetase requires cooexpression with an enoyl reductase. CHEMBIOCHEM, 9(4), 585-594. https://doi.org/10.1002/cbic.200700390
Cox, R. J. (2008). The biosynthesis of polyketides, acyl tetramic acids and pyridones by filamentous fungi. In Exploitation of Fungi: Symposium of the British Mycological Society Held at the University of Manchester September 2005 (pp. 25-44). Cambridge University Press. https://doi.org/10.1017/CBO9780511902451.004
2007
Beltran-Alvarez, P., Cox, R. J., Crosby, J., & Simpson, T. J. (2007). Dissecting the component reactions catalyzed by the actinorhodin minimal polyketide synthase. Biochemistry, 46(50), 14672-14681. https://doi.org/10.1021/bi701784c
Cox, R. J. (2007). The biosynthesis of polyketides, tetramic acids, and pyridones in fungi. In A. Rimando, & S. Baerson (Eds.), Polyketides Biosynthesis, Biological Activity, and Genetic Engineering (pp. 33-47). (ACS Symposium Series; Vol. 955).
Wong, U., & Cox, R. J. (2007). The chemical mechanism of D-1-deoxyxylulose-5-phosphate reductoisomerase from Escherichia coli. Angewandte Chemie , 46(26), 4926-4929. https://doi.org/10.1002/anie.200700647, https://doi.org/10.1002/ange.200700647
Hothersall, J., Wu, J., Rahman, A. S., Shields, J. A., Haddock, J., Johnson, N., Cooper, S. M., Stephens, E. R., Cox, R. J., Crosby, J., Willis, C. L., Simpson, T. J., & Thomas, C. M. (2007). Mutational analysis reveals that all tailoring region genes are required for production of polyketide antibiotic mupirocin by Pseudomonas fluorescens: Pseudomonic acid B biosynthesis precedes pseudomonic acid A. Journal of Biological Chemistry, 282(21), 15451-15461. https://doi.org/10.1074/jbc.M701490200
