Showing results 121 - 130 out of 192
2011
Fukuda, D., Haines, A. S., Song, Z., Murphy, A. C., Hothersall, J., Stephens, E. R., Gurney, R., Cox, R. J., Crosby, J., Willis, C. L., Simpson, T. J., & Thomas, C. M. (2011). A natural plasmid uniquely encodes two biosynthetic pathways creating a potent anti-MRSA antibiotic. PLOS ONE, 6(3), Article e18031. https://doi.org/10.1371/journal.pone.0018031
Murphy, A. C., Fukuda, D., Song, Z., Hothersall, J., Cox, R. J., Willis, C. L., Thomas, C. M., & Simpson, T. J. (2011). Engineered thiomarinol antibiotics active against MRSA are generated by mutagenesis and mutasynthesis of pseudoalteromonas SANK73390. Angewandte Chemie , 50(14), 3271-3274. https://doi.org/10.1002/anie.201007029, https://doi.org/10.1002/ange.201007029
2010
Heneghan, M. N., Yakasai, A. A., Halo, L. M., Song, Z., Bailey, A. M., Simpson, T. J., Cox, R. J., & Lazarus, C. M. (2010). First heterologous reconstruction of a complete functional fungal biosynthetic multigene cluster. CHEMBIOCHEM, 11(11), 1508-1512. https://doi.org/10.1002/cbic.201000259
Skellam, E. J., Hurley, D., Davison, J., Lazarus, C. M., Simpson, T. J., & Cox, R. J. (2010). Mutation of key residues in the C-methyltransferase domain of a fungal highly reducing polyketide synthase. Molecular BioSystems, 6(4), 680-682. https://doi.org/10.1039/b923990a
Wattana-amorn, P., Williams, C., Ploskoń, E., Cox, R. J., Simpson, T. J., Crosby, J., & Crump, M. P. (2010). Solution structure of an acyl carrier protein domain from a fungal type i polyketide synthase. Biochemistry, 49(10), 2186-2193. https://doi.org/10.1021/bi902176v
Cox, R. J., & Simpson, T. J. (2010). Fungal type I polyketides. In Comprehensive Natural Products II: Chemistry and Biology (Vol. 1, pp. 347-383). Elsevier Ltd..
Fisch, K. M., Skellam, E., Ivison, D., Cox, R. J., Bailey, A. M., Lazarus, C. M., & Simpson, T. J. (2010). Catalytic role of the C-terminal domains of a fungal non-reducing polyketide synthase. Chemical communications, 46(29), 5331-5333. https://doi.org/10.1039/c0cc01162b
Cox, R. J., Halo, L. M., & Heneghan, M. N. (2010). Expression of complete fungal biosynthetic gene clusters by promoter replacement in Aspergillus oryzae. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
Wu, J., Zhang, H. B., Xu, J. L., Cox, R. J., Simpson, T. J., & Zhang, L. H. (2010). 13C Labeling reveals multiple amination reactions in the biosynthesis of a novel polyketide polyamine antibiotic zeamine from Dickeya zeae. Chemical communications, 46(2), 333-335. https://doi.org/10.1039/b916307g
2009
Evans, S. E., Williams, C., Arthur, C. J., Płoskoń, E., Wattana-amorn, P., Cox, R. J., Crosby, J., Willis, C. L., Simpson, T. J., & Crump, M. P. (2009). Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). Journal of molecular biology, 389(3), 511-528. https://doi.org/10.1016/j.jmb.2009.03.072
